Volume 2  |  Issue 1  |  January 2020


We invite you to explore volume two, issue one of the CBSD Quarterly Courier! In this issue, we share some exciting news, highlight one of our very own core facilities and project holders, and introduce you to one of our talented Core Facility Fellows. As always, we share recent publications citing the use of CoBRE resources. If you have suggestions for content, simply reply to this email or connect with any one of the CBSD team members

News: We are growing!

Featured Core Facility: Biospectroscopy Core Research Laboratory

Project Highlight: Dong Wang
Student Spotlight: Michelle Nemetchek

Save the date: CBSD CoBRE Research Symposium

Recent Publications

We are growing!

In the last issue, we noted there was an exciting announcement for our community. Well, the wait is over! We are thrilled to share with you that the Integrated Structural Biology Core (ISBC) is growing! 
Image of ISB 015 contruction progress
For several years, CBSD has had the goal of creating a biochemistry and tissue culture facility in ISB 015 so that the ISBC will have the capacity to conduct macromolecular expression, purification and biophysical analysis for UM faculty investigators, their students and fellows. The plans (below) have finally come to fruition with the support of the Office of the Vice President for Research and Creative Scholarship, using IDC cost returns generated from grants submitted through the CBSD. The first phases of construction (right) are underway!

We will continue to provide updates on the construction progress through this quarterly newsletter and our website.
Image of construction plans for ISB 015
TIRF Microscope based on Nikon TE

Featured Core Facility: Biospectroscopy Core Reseach Laboratory (BCRL)

To kick off 2020, we would like to bring your attention to CBSD’s Biospectroscopy Core Research Laboratory (BCRL). Directed by Professor Sandy Ross and managed by Dr. Zifan Wang, the Core offers consultation, experimental design, measurement, and data analysis on a collaborative or contractual basis. Services include imaging comprising confocal, differential interference contrast, phase contrast, bright field, and total internal reflection fluorescence microscopy; steady-state absorption and fluorescence; and time-resolved techniques comprising anisotropy, fluorescence and phosphorescence intensity decay, Förster Resonance Energy Transfer (FRET), Single-Molecule FRET (smFRET), Time-Resolved Emission Spectra (TRES), Fluorescence Correlation Spectroscopy (FCS), Dual-focus Fluorescence Correlation Spectroscopy (2fFCS), and Fluorescence Lifetime Imaging (FLIM).
Read the full highlight on our website.
In July 2019, Drs. Ross and Harmen Steele organized a two-day Time-Correlated Single-Photon Counting (TCSPC) Fluorescence Workshop that featured presentations by nationally and internationally renowned investigators. The photo above was taken during the Workshop.

Project Highlight: Dong Wang

Image of Dr. Dong WangOur first project highlight of 2020 is of Dr. Dong Wang from the Department of Chemistry and Biochemistry. His research interests lie with the design of biomimetic and bioinspired complexes based on first-row late-transition metals for catalyzing energy-demanding reactions such as the functionalization of inert hydrocarbons and the splitting of water to generate chemical fuels. He is also interested in capturing and characterizing reactive high-valent metal-oxo intermediates involved in these catalytic systems.
Read the full highlight on our website.

Student Spotlight: Michelle Nemetchek

Image of Michelle NemetchekDuring her year as a Core Fellow in the Integrated Structural Biology Core (ISBC), Michelle gained several valuable structural biology skills. These ranged from protein expression and purification to X-ray crystallography, and finally to single-particle cryo-electron microscopy.
Read the full spotlight on our website.
9th Annual CBSD CoBRE Research Symposium - Sept. 18-20, 2020 Double Arrow Lodge in Seeley Lake, MT

Save the date: CBSD CoBRE Research Symposium

As you may have seen, the 9th Annual CBSD CoBRE Research Symposium will occur Sept. 18-20, 2020, at the Double Arrow Lodge in Seeley Lake, MT. The Symposium provides us with the unique opportunity to come together as a research community to discuss the latest research in our laboratories supported by CBSD. We sincerely hope you will join us in September!

Registration will open in June 2020. Contact Sara Jestrab (sara.jestrab@umontana.edu) with questions or to verify that you are on the email communication.

Recent Publications Supported by the CBSD

View all publications citing CBSD CoBRE. If you are working on a manuscript that has used CBSD CoBRE resources please remember to cite P20GM103546.
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We want to extend a special thank you to our newsletter contributors this month: Sara Jestrab, Michelle Nemetchek, Sandy Ross, Stephen Sprang, Harmen Steele, Dong Wang and Zifan Wang. CBSD would also like to thank it's newsletter content reviewers: Heidi Boggs, Bruce Bowler, Sara Jestrab and Stephen Sprang.
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