PolySciTech Products In Literature
PLCL from PolySciTech used in development of tissue engineering for repair of torn rotator cuff and other injuries
Depending on the nature and location of an injury, healing may be difficult if not impossible as some tissues have either slow regeneration rates or do not heal at all unless certain conditions are met. An example of this is a torn rotator cuff, a common shoulder injury, where the damaged tendons do not heal on their own. Recently, researchers at Novartis, Columbia University, the University of Pennsylvania, and the University of Connecticut used Poly(lactide-co-caprolactone) PLCL from PolySciTech as part of their development of tissue engineering repairs for cartilage and ligaments. This research holds promise to improve traumatic wound repair in the future. Read more: Prabhath, A., Vernekar, V.N., Esdaille, C.J., Eisenberg, E., Lebaschi, A., Badon, M., Seyedsalehi, A., Dzidotor, G., Tang, X., Dyment, N. and Thomopoulos, S., 2022. "Pegylated insulin-like growth factor-1 biotherapeutic delivery promotes rotator cuff regeneration in a rat model." Journal of Biomedical Materials Research Part A.
|
|
PLGA-PEG-PLGA from PolySciTech used in development of Rapamycin delivery system
Rapamycin is a macrolide exhibiting potent antitumor and immunosuppressive activity. Unfortunately, it has quick clearance and lacks targeted delivery for many applications. Recently, researchers used PLGA-PEG-PLGA (AK016) from PolySciTech to create rapamycin-loaded nanoparticles inside of microspheres. Researchers tested the application of this delivery system in the treatment of hemangiomas. This research holds promise to provide the improved application of rapamycin against a variety of disease states. Read more: Li, Haitao, Xin Wang, Xiaonan Guo, Qingkun Wan, Yunfei Teng, and Jianyong Liu. "Development of rapamycin-encapsulated exosome-mimetic nanoparticles-in-PLGA microspheres for treatment of hemangiomas." Biomedicine & Pharmacotherapy 148 (2022): 112737.
|
|
Print what you want with the latest bioresorbable polymer technology. AKiNAfil™ bioresorbable PLGA polymers reformatted in standardized 1.7 mm filament are available in a variety of lengths. The PLGA polymers are co-formulated with FDA-GRAS and biocompatible acetyltriethylcitrate (ATEC) plasticizer for improved processability and biorelevant degradation properties to be used in a wide array of biomedical applications. |
|
|
Browse through our searchable list of research
that reference the use of PolySciTech products.
|
|
|
PolySciTech Division of Akina, Inc. (www.polyscitech.com) provides a wide array of biodegradable polymers and other research supplies. Visit our website to find out more.
|
|
|
|
