PolySciTech Products In Literature
PLGA from PolySciTech used in development of cancer immunotherapy platform
Immunotherapy is a process by which the immune system is triggered to attack the cancer cells directly. Researchers at Sungkyunkwan University used PLGA from PolySciTech to create microparticles encapsulated with tumor lysate as a means to initiate an immune response against cancer. This research holds promise to improve immunotherapy against cancer. Read more: Lee, Jae Ah, Jung Min Shin, Seok Ho Song, Chan Ho Kim, Soyoung Son, Sol Shin, and Jae Hyung Park. "Recruitment of dendritic cells using ‘find-me’ signaling microparticles for personalized cancer immunotherapy." Biomaterials (2022): 121412.
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PLGA-PEG-PLGA Thermogel from PolySciTech used in study to understand neointimal hyperplasia.
Neointimal hyperplasia is a process by which injured vessels will initiate the in-growth of tissue. This process is particularly problematic during stenosis as the growing tissue blocks the interior of the stent and re-closes the vessel. Recently, researchers from the University of Virginia and The Ohio State University used PLGA-PEG-PLGA (AK012) from PolySciTech to deliver an EZH1/2 inhibitor (UNC1999) as a way to model healing with this pathway blocked off. This understanding of the vessel healing process can assist with designing more effective means of stenosis. Read more: Zhang, Mengxue, Go Urabe, Hatice Gulcin Ozer, Xiujie Xie, Amy Webb, Takuro Shirasu, Jing Li et al. "Angioplasty induces epigenomic remodeling in injured arteries." Life Science Alliance 5, no. 5 (2022).
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Print what you want with the latest bioresorbable polymer technology. AKiNAfil™ bioresorbable PLGA polymers reformatted in standardized 1.7 mm filament are available in a variety of lengths. The PLGA polymers are co-formulated with FDA-GRAS and biocompatible acetyltriethylcitrate (ATEC) plasticizer for improved processability and biorelevant degradation properties to be used in a wide array of biomedical applications. |
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Browse through our searchable list of research
that reference the use of PolySciTech products.
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PolySciTech Division of Akina, Inc. (www.polyscitech.com) provides a wide array of biodegradable polymers and other research supplies. Visit our website to find out more.
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